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The difference between 0.9% and 1.1% may appear minor but is significant for concentration-sensitive peptides

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Ibuprofen was shown to attenuate the metabolism of AEA by FAAH in rat brain 71

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Toxic effects may manifest as testicular atrophy, decreased sperm count and motility in males, and impaired follicular development, luteal insufficiency, and hormonal cycle disruptions in females [75, 76]

Since the body cannot synthesize Vit B9, it must be supplemented exogenously and gastrointestinal dysfunction, a prominent dysautonomic feature of MSA, may explain such deficiency