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CD4 + Th17 cells are the primary source of IL-17 in psoriatic lesions, and IL-17A the core subtype of this cytokine drives the inflammatory response in keratinocytes
10.1371/journal.pone.0306572 7
Tipo de presentacin: 30 cpsulas
doi:10.1152/PHYSREV.00003.2008 9
increasing the expression of mitofusin 1 (MFN1) and mitofusin 2 (MFN2)
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Other considerations include a small increased risk of lower limb amputation and bone fractures observed primarily with canagliflozin in certain trials
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