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Those with active cancer should consult an oncologist, as growth-factor modulation could theoretically influence tumor growth
For instance, the bacterial metabolite Pseudomonas quinolone signal (PQS) activates host histidine methyltransferase carnosine-N-methyltransferase (CNMT), leading to epigenetic upregulation of transferrin receptor 1 (TFR1) and enhanced iron uptake, thereby promoting ferroptosis (Jia et al., 2025)
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Additionally, B12 has been shown to elevate your mood which can also be helpful in making you want to work out
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