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10.3892/etm.2020.9199 176 ZhangL.LiY
These miRNAs reside in intronic regions within SREBP-1 and 2, the key transcriptional regulators of lipid metabolism 87 , and control the expression of carnitine O -octanoyltransferase (CROT), CPT1A, hydroxyacyl coenzyme A (hydroxyacyl-CoA) dehydrogenase subunit beta (HADHB), and AMPK, targeting their 3 UTR 88
Molecular weight verification confirms the correct peptide sequence
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The exact pathways for its skin-lightening effects are not fully understood but may involve inhibition of melanin synthesis
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