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The hHPN RS mutant was engineered to produce hepsin without functional activity by introducing two specific mutations in critical regions of its proteolytic activity
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10.1093/jnci/89.7.480 15 DolatabadiS.OskueiS
For optimal results, clinicians should consider individualized approaches, monitor for possible adverse effects, and ensure supplementation is integrated into a broader treatment plan grounded in evidence-based practice
(PubMed) Percival SS
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