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Tirzepatides dual-action mechanism, targeting both GLP-1 and GIP receptors, offers broader metabolic benefits, which may contribute to greater and more sustained weight loss compared to Semaglutide GLP-1, which primarily targets GLP-1 receptors
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doi: 10.1039/C9FO00201D 20
Orlistat works by blocking the absorption of dietary fat and can promote weight reductions of up to 5% after 12 weeks of use
Researchers note that participants can observe weight loss, which could have led them to censor information and take action to stop or switch medications
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