Higher doses of tirzepatide helped patients with obesity lose roughly 20.9% of their body weight on average in late-stage studies, when analysing all patients regardless of discontinuations
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CVS Caremark denies coverage for patients with conditions that would prevent weight loss: uncontrolled hypothyroidism, Cushing's syndrome, or medications known to cause weight gain (antipsychotics, corticosteroids) that cannot be discontinued
PMID: 9186261