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Despite the strong correlation between growth within 3D gels and tumorigenicity [25], it remains unclear why TICs are the exclusive tumor cells capable of growing in this condition, while non-tumor lymphoid cells do not

Reproduction 103 (1), 1726 (1995) Harborne, JB.: Do natural plant phenols play a role in ecology

Apr-Jun 2014;51(2):144-50

However, the key limitation is the lack of long-term human safety data

it modulates the expression of over 4,000 human genes, including those responsible for inflammation control, DNA repair, collagen and elastin synthesis, antioxidant defense, and stem cell activity

No human RCT in IBD or leaky gut has been completed