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A buildup of uric acid causes crystals to pile up in soft tissue and joints

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Presented for research literature review only Murata H et al

(2021) (20), treatment of pregnant females on gestational days 18 resulted in dose-dependent reductions in sperm counts and increases in oxidative stress markers in male progeny at postnatal day 60 (PND 60), while nuclear maturation of germ cells was unaffected

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Gamma-glutamyl transpeptidase deficiency leads to glutathionuria, glutathionemia, growth failure, cataracts, lethargy, shortened life span, and infertility