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Figure 3 After the diagnosis of GSSD, the infant continued to receive l-carnitine to improve her metabolism, oral sodium bicarbonate to correct acidosis, and oral vitamins C and E to prevent oxidative stress
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Future studies should optimize treatment parameters, including formulation, dosage, timing of administration, and assessment of brain biodistribution and explore multi-target strategies combining redox modulation with interventions that directly engage synaptic plasticity, neurotrophic signaling or critical developmental windows, to achieve functional behavioral outcomes in ASD
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In all tissues (muscles, organs especially the liver ) mainly adenosylcobalamin is found In the blood and spinal cord methylcobalamin and hydroxocobalamin are found in equal measure (10) In the cells both adenosylcobalamin and methylcobalamin are required, which can easily be transformed into each other Vitamin B12 Active Ingredients in Supplements Previously, in vitamin B12 supplements synthetic cyanocobalamin and hydroxocobalamin were mainly used in B12 injections
Medinas et al., 2018)
