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IUPHAR review Glucagon-like peptide-1 (GLP-1) and substance use disorders: an emerging pharmacotherapeutic target

doi: 10.1177/11795514221090244 29 ShapiroS

Collectively, these data reveal that exendin 2029 acts as a key sequence in inducing analgesia in CAP-elicited nociceptive behaviors in mice without causing hyperthermia, and this analgesic effect is mediated by exendin 2029 directly inhibiting CAP-induced TRPV1 activation but not proton-induced TRPV1 activation

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Batista AF, Bodart V, De FFG, Ferreira ST