A GLP-1 receptor agonist medication may help patients with psoriasis.[ref] Related article: T Cell Exhaustion Asthma symptoms decrease: Asthma exacerbations also decreased in patients on GLP-1 receptor agonist medications.[ref] ( Related article : Asthma genes) Dementia and Alzheimers Prevention: In animal studies, infusions of GLP-1 decrease amyloid-beta levels and prevent neuronal cell death.[ref] Dysregulation of glucose entry into the brain is one hallmark of Alzheimers disease, tying together insulin resistance, GLP-1, and dementia.[ref][ref] GLP-1 receptor agonist drugs, such as liraglutide, are being studied for Alzheimers disease.[ref] Studies using data from diabetes patients showed a significant decrease in dementia for those on GLP-1s vs other diabetes medications
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Although, identifying interventions to slow down muscle wasting and loss of strength in older populations remains challenging, evidence is emerging that specific types of physical activity and nutritional intake may affect muscle loss with aging
PBS Key take-aways Step-before-GLP-1 PBS now demands that an SGLT2-i be trialled (unless contraindicated) and either: caused intolerance, or failed to achieve 0.5 % (5 mmol/mol) HbA1c reduction after 6 months
Vinification: Spontaneous alcoholic fermentation in a concrete tank, 15% whole vat, with temperatures between 18-26 C