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Metabolically active and associated with increased risk of cardiovascular disease, type 2 diabetes, and systemic inflammation

& Kasinski, A

BRCA1, which regulates cell cycle progression, DNA damage signalling and repair, and maintenance of genomic integrity, interacts with NRF2 either directly, through its ETGE motif, preventing KEAP1-dependent ubiquitination of NRF2 and protecting cells against OS, or indirectly, through the interaction with CBP or with c-Myc [186]

Nakhleh, A., & Shehadeh, N

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Este guia resume o estado da investigao de forma estritamente documental, sem quaisquer afirmaes sobre a aplicao em humanos