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doi: 10.1161/ATVBAHA.107.159327 39 MenghiniRCasagrandeVRizzaSFedericiM
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GLP-1 medications generally aren't appropriate with: Personal/family history of medullary thyroid carcinoma (MTC) Multiple Endocrine Neoplasia type 2 (MEN 2) History of pancreatitis Severe gastroparesis or GI motility disorders Pregnancy, trying to conceive, or breastfeeding A history of eating disorders (requires careful evaluation) Josh reviews your full history at your consult to confirm treatment is safe for you
This suggests that GLP-1-induced cardioprotection may be related to the inactivation of the ER stress signaling pathway [78]
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