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Considering that the upregulation of these checkpoints may occasionally be linked to T-cell exhaustion or depletion [268, 269], the mechanisms that promote the induction of T-cell exhaustion are not completely clear
CXCR4/CXCL12 mediate autocrine cell- cycle progression in NF1-associated malignant peripheral nerve sheath tumors
GLP-1 receptors (GLP-1R) are expressed in pulmonary epithelial cells, airway smooth muscle, alveolar macrophages, and pulmonary vasculature [3, 4]
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