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PMID: 7817664

This is attributed to its increase in fibroblast proliferation [3, 22]

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Beyond the GI profile, the NEJM Phase 2 trial also logged back pain as a low-rate adverse event across dose groups, and a small number of pancreatitis and gallbladder events were recorded at higher doses the full NEJM 2023 retatrutide obesity trial adverse events line-listing (abdominal pain, back pain, pancreatitis, gallbladder) is why many researchers pair the stomach pain discussion with back pain when reviewing the data

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Some studies on similar injectable medications, like insulin and other GLP-1 agonists, have shown that the absorption rate can vary slightly by location