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To minimize gastrointestinal side effects, doses are gradually increased over several weeks to months

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You will need to pair the medication with a healthy diet and exercise (like the Blue Sky MD Asheville weight loss program)

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Keep the vial dry and sealed

In August 2025, a review found that flavonoids, which contribute to bitter flavors in, say, citrus or hops, can stimulate GLP-1 release, too