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the hyperphosphorylation of tau proteins leads to the disruption of microtubule structure and affects mitochondrial axonal transport, exacerbating the neuronal energy crisis (Meng et al., 2024)
Alginate-based antacids (such as those containing sodium alginate and sodium bicarbonate) can provide short-term symptomatic relief and are available over the counter
Under conditions of high partial pressure of oxygen, radicals of carotenoids, Car , originating from the reaction of ROS with a carotenoid molecule by hydrogen abstraction may further react with dioxygen according to the reaction (Young and Lowe 2001
In patients with grade 1 or 2 encephalopathy on a scale of 0 (minimal) to 4 (comatose), the transplant-free survival rate is higher when acetyl-cysteine is given compared with placebo, but this benefit does not extend to patients with a higher grade of encephalopathy
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Neurological symptoms may start improving within 12 weeks, but longstanding complications can require 36 months of treatment, with some damage potentially irreversible
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