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Despite proven efficacy, both treatments are limited by inconsistent responses, the need for ongoing use, recurrence after discontinuation, and side effects such as scalp irritation and sexual or hormonal issues [6, 7]

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Tirzepatide helps manage hunger and blood sugar, but the quality of your nutrition and physical activity still matters

Some report improved sleep quality or subtle increases in energy, though these could reflect placebo effects

In the REDEFINE 1 trial, CagriSema produced 20.4% weight loss versus 14.9% for semaglutide alone