Neurological symptoms range from impaired cognitive function, depression, seizures, and premature aging of neurons, to paresthesias, painful dysesthesias, and thermal sensations (6, 11, 16, 58)
Disadvantages: No topical cosmetic applications, not naturally occurring in plasma
boidinii strain AOU-1 in SP liquid media
Despite the exposure of mitochondria to the production of oxidants, the presence of an effective antioxidant system, of which mitochondrial GSH (mGSH) is a key component, prevents or repairs oxidative damage that occurs during normal aerobic metabolism [57]
Regulatory status matters because cosmetics, compounded peptides, investigational products, and approved prescription drugs are not evaluated under the same standards
An important question that remains is if targeting UndP utilisation pathways is a viable strategy for antibiotic development