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Hydroxocobalamin provides a longer-acting effect compared with oral B12 supplements, which reduces the frequency of dosing

Not much yet, practically speaking

The doses used in those models, when allometrically scaled to humans using a standard body surface area conversion, suggest a range of roughly 200 to 500 mcg per day

A fragment does not automatically have the same effects or safety profile as the whole

But you should talk to your doctor before making any changes to your treatment routine

Loading uses higher, more frequent doses ( 22.5 mg twice weekly ) to rapidly build tissue saturation and initiate the healing cascade