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When used together, particularly alongside insulin or sulphonylureas, there is a potential increased risk of hypoglycaemia requiring careful monitoring

FGF21 and FGF19 receptors, which have pleiotropic effects on liver steatosis, inflammation and fibrosis

Mounjaro is FDA-approved to treat type 2 diabetes, while Zepbound is FDA-approved for chronic weight management and obstructive sleep apnea

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Brain Response (Appetite Centers) GLP-1 medications may affect appetite pathways involved in fullness and hunger cues