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[22] [23] Versus DPP-4 inhibitors (such as sitagliptin), GLP-1 receptor agonists produce greater HbA1c reductions and weight loss, with some offering proven cardiovascular benefits

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While PAP does lead to greater reductions in AHI and higher rates of complete treatment response when compared to MADs, patients are generally able to better tolerate MADs compared to PAP, with higher patient-reported compliance [36]