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Berberine, a natural alkaloid and key bioactive constituent of traditional Chinese medicinal herbs, suppresses tubular pyroptosis, thereby mitigating renal inflammation and interstitial fibrosis in DKD (170)

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All 16 rats underwent testing 1, 2, 3, and 4 h after administration of 30 mg/kg PO, Atlas987 combined with 10 mg/kg PO paroxetine (see Figure 3)

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