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NRF2 is a crucial transcription factor involved in the regulation of inflammatory responses and oxidative stress

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For most patients, feeling colder whilst taking GLP-1 medications is commonly reported and often related to weight loss rather than a direct drug adverse effect

9 GLP-1 synthesis is not exclusive to the endocrine system, as it can also originate from neurons within the CNS

GLP-1-based therapies for type 2 diabetes: from single, dual and triple agonists to endogenous GLP-1 production and L-cell differentiation