As of January 6, 2025 here is a list of approved and pending new GLP-1 agonists class of medications that can help manage Type 2 diabetes and obesity: Ozempic (semaglutide) Approved - A weekly injectable GLP-1 receptor agonist that helps regulate blood sugar and suppress appetite, promoting weight loss in addition to managing type 2 diabetes
A protective effect of GLP-1 agonists on blood vessels has been demonstrated, as evidenced by the reduction of non-fatal and fatal stroke incidence by 15% and 19%, respectively, in patients with T2DM treated with GLP-1 agonists [43]
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In this study the patients received one protease inhibitor (indinavir or ritonavir) in combination with two nucleoside analogs (lamivudine plus zidovudine or plus stavudine), suggesting that the HAART ameliorates the oxidative alterations related with HIV-1 infection [43]
And at the molecular level, GLP-1 receptor agonists appear to directly inhibit platelet aggregation, reduce inflammatory markers, and improve endothelial function, all of which should theoretically protect against clots
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