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Neurodegenerative diseases (NDDs) are related with the presence of abnormal protein folding, aggregation and deposition in the brain, which lead to alterations in neural functioning, and ultimately, neural cell death (66)

Maintaining an optimal level of glutathione appears to be important for supporting cognitive function, especially during aging.* The normal process of aging is associated with a decrease in glutathione activity, which can result in increased oxidative activity.* Less than an optimum level of glutathione is observed in individuals experiencing a decline in cognitive function.* Conversely, individuals who live to 100 tend to have higher glutathione activity.*

Department of Agriculture Human Nutrition Research Center at Tufts University in Boston