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All experiments were approved by the Institutional Animal Care and Use Committee at the Albert Einstein College of Medicine (Protocol #20140107)

Specifically, they increase glucose-dependent insulin secretion, suppress glucagon, delay gastric emptying (which prolongs the feeling of fullness after meals), and reduce appetite by acting on brain centers that control hunger

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When the body perceives insufficient energy intake, it prioritizes vital functions over non-essential processes like hair growth

It affects vascular biology, inflammation, energy metabolism, body composition, and possibly brain aging

Targeting 5 mg/mL requires 4.0 mL, and 2.5 mg/mL needs 8.0 mL