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The Dual-Energy X-ray Absorptiometry (DXA) substudy data from the landmark clinical trials reveals exactly how much muscle tax each peptide extracts versus how much actual fat they burn

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The three paralogs show preferential tissue expression: - ERRalpha (ESRRA) : ubiquitous expression with enrichment in high-energy-demand tissues skeletal muscle (type I oxidative fibers), myocardium, brown adipose tissue (BAT), renal cortex, liver

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These effects have led to the development of GLP-1 agonists as a treatment for type 2 diabetes