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marketed for diabetes as Mounjaro and for weight management under trade names such as Zepbound) Tirzepatide combines GLP-1 and GIP receptor agonism and has shown the largest average weight losses of any medication to date

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These medications acknowledge what women have known intuitively: that perimenopausal weight gain isnt simply about eating less and moving moreits about addressing the complex metabolic and hormonal changes occurring in their bodies