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Protein and Sport: Alternative Sources and Strategies for Bioactive and Sustainable Sports Nutrition
Key principles include: Maintaining a modest caloric deficit (300-500 calories below maintenance) to prevent rapid weight regain Emphasizing protein intake (1.2-1.6 g/kg body weight) to preserve lean muscle mass and promote satiety, with individualization for those with chronic kidney disease or other conditions requiring protein modification Incorporating high-fiber foods to enhance fullness and support glycemic control Practicing mindful eating and portion awareness to compensate for increased appetite Limiting ultra-processed foods and added sugars that promote overconsumption Physical activity plays a crucial role in weight maintenance and glucose regulation after stopping tirzepatide
Post hoc analysis of SUSTAIN 6 and PIONEER 6 trials suggests that people with type 2 diabetes at high cardiovascular risk treated with semaglutide experience more stable kidney function compared with placebo
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Enzymes such as Dipeptidyl Peptidase-4 (DPP-4) and Neutral Endopeptidase (NEP) contribute to this process, yielding inactive biological fragments (23)(30) Semaglutide, Serum, and tissue proteases metabolize the polypeptide into amino acids, clearing it from the system and preventing accumulation (23)(21)
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