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12, June 2018

Normally in humans, one of the main antioxidants in plasma is uric acid.UA is a hydrophilic antioxidant generated during the metabolism of purine nucleotides and accounts nearly for 66% of the total oxygen scavenging activity in the blood serum

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We believe that significant efforts should be put into investigating in greater detail the pathways shared by eryptosis and erythronecroptosis, like caspase-8, ROS signaling, Fas/FasL signaling, to collect more evidence on the interplay between these erythrocyte-specific RCDs

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