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The ORF2 reading frame does not contain an AUG translation initiation codon and as such translation through ORF2 requires the failure of the ribosome to terminate at the end of ORF1 and instead shift to the +1 reading frame
A sustained-release implant model requires different controls and sampling schedules than an acute-injection model
Yes, from a research perspective, the loading phase is critical
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Nuclei were counterstained with 4,6-diamidino-2-phenylindole
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