Ibuprofen 400 mg or acetaminophen 500 mg as needed Limit to 3-4 days per week to avoid medication overuse headache Take with food to reduce GI side effects on top of GLP-1 nausea Step 6: Provider-directed evaluation
The 28-day rule Once you puncture the vial's rubber stopper with a needle for the first time, the clock starts
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Then, depressive and manic symptoms, treatment acceptability, gastrointestinal and other side effects are assessed at baseline (prior to randomization) and weekly, whereas stool samples to evaluate microbiome composition are obtained at baseline and 3 and 6 months [332]