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Currently, there are a total of ten FDA-approved indications for hGH therapy [5]: Growth hormone deficiency in children and adults (GHD) Growth failure due to chronic renal insufficiency Muscle wasting due to AIDS Noonan syndrome Prader-Willi syndrome Short bowel syndrome (SBS) Short stature homeobox (SHOX)-containing gene deficiency Small-for-gestational-age infants Turner syndrome Recombinant hGH therapy can effectively and dose-dependently increase serum GH levels, hence its use in managing the symptoms of GHD in children and adults

6 PMC (2022)Reduced-calorie diet with NNMT inhibition establishes a distinct microbiome in DIO mice

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This MEOS induction increases ethanol clearance speed in established heavy drinkers compared to occasional drinkers at equivalent BAC levels

GLP-1driven rapid weight loss and the rise in skin laxity further accelerate interest

doi: 10.1038/nchembio.2238 110 WenzelSETyurinaYYZhaoJSt CroixCMDarHHMaoGet al