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Insurance companies have not been as generous in covering this medication, and paying over $1,000 per month out-of-pocket is not feasible for most patients. Sources: Novo Nordisk (Wegovy)
One of the main issues is the rebound effect : when the drug is discontinued, there is a strong tendency to regain the lost weight
Fibrosi epatica : accumulo progressivo di tessuto cicatriziale nel fegato in risposta al danno cronico
Overall, the findings underscore the mortality benefit of semaglutide and reinforce that obesity and overweight elevate mortality risks through several etiologies, which can be modified with potent therapies like semaglutide
Real-world use of oral semaglutide in adults with type 2 diabetes in the PIONEER REAL Netherlands multicentre, prospective, observational study
Criteria include a BMI of 40 kg/m or above, or 35 kg/m or above with a significant obesity-related condition such as type 2 diabetes or hypertension
