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For neurogenesis specifically, P21 covers a pathway the others do not
These mechanisms are complementary rather than competitive, potentially making combination use attractive for anti-aging focused researchers
References Chang, C
Its N-terminal domain inhibits lipoprotein lipase (LPL), raising plasma TG levels
It neutralises free radicals through reduction reactions, donating electrons to unstable molecules and preventing oxidative damage to proteins, lipids, and DNA
The big innovation with GLP-1 medications was figuring out how to stop the peptide from being broken down so quickly
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