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Because the DECR1 encoded enzyme is localized to the mitochondria and requires NADPH as a co-factor
Karniski, L
doi: 10.1016/j.foodchem.2019.125328 Summary Keywords antioxidants, breast cancer, breast cancer prevalence, dietary antioxidants, oxidative stress, reactive oxygen species, breast cancer diagnosis, breast cancer epidemiology Citation Adegoke AM, Igomu GO, Usin SG and Sekhoacha MP (2026) Oxidative stress and antioxidants in breast cancer: a double-edged sword
LCLT, a more bioavailable form of L-Carnitine, works by transporting fatty acids into the mitochondria where they are utilized for energy production
Causes: (a) Bland: Oral contraceptive pills, anabolic steroid, androgens (b) Inflammatory: Allopurinol, co-amoxiclav, carbamazepine (c) Ductal: Chlorpromazine, flucloxacillin Steatosis: Hepatotoxicity may manifest as triglyceride accumulation which leads to either small droplet (microvesicular) or large droplet (macrovesicular) fatty liver
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