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Furthermore, the studys sole focus on suicidal ideation as the primary outcome is less suitable for retrospective studies, where patients more commonly present with major depression or anxiety, potentially accompanied by suicidal ideation, rather than with suicidal ideation alone

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By acting on the brain, they decrease hunger and food cravings, making it easier to follow regular eating patterns and reduce overall calorie intake

Spironolactone's Effect on CYP3A4 Spironolactone is a known substrate and weak-to-moderate inhibitor of CYP3A4

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