Mechanistic insights from non-AD neuroinflammatory systems provide complementary evidence: interferon- (IFN-) robustly induces PD-L1 expression in human astrocytes and microglia, establishing a checkpointredox interface that suppresses excessive oxidative injury (Smith et al., 2023
Finally, the observed changes in prescribing behavior occurred at the same time as the CVS Caremark formulary change
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