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The largest amounts are found in the skeletal and cardiac muscles, which cannot produce their carnitine and must instead get it from plasma
Microbiome 9 (1), 235
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The effect of acylcarnitine on insulin sensitivity is also related to the saturation of acylcarnitine, with myotubes incubated with C16-carnitine exhibiting reduced insulin sensitization, whereas the accumulation of oleoylcarnitine (C18:1-carnitine) and linoleoylcarnitine (C18:2-carnitine) increases insulin sensitization [77]
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