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doi: 10.31887/DCNS.2009.11.2/cqiu 114 PlassmanBLLangaKMFisherGGHeeringaSGWeirDROfstedalMBet al
Another key question is whether psychiatric effects are direct or secondary to metabolic improvements
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The cyclisation of Melanotan II addresses this limitation through a 23-atom lactam bridge connecting the side chains of an Asp residue and a Lys residue, constraining the central His-D-Phe-Arg-Trp recognition motif into the receptor-binding conformation
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