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While the patient groups did not differ by sex, M/M were of slightly lower age relative to both HC and SA and, unsurprisingly, higher fractional exhaled nitric oxide (FeNO) and lower FEV 1 (% predicted) were observed across groups from HC to SA
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In the United States, the FDA Biomarker Qualification Program was designed to formalize the use of biomarkers in therapeutic development, but progress has been slow
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