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When you take Vitamin C, for example, it eventually becomes "spent" after neutralizing a free radical

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Furthermore, there were no drop outs during the study period

Effects of L-carnitine on erythrocyte acyl-CoA, free CoA, and glycerophospholipid [PMID: 9497180] Laboratory literature summary: Effects of L-carnitine on erythrocyte acyl-CoA, free CoA, and glycerophospholipid acyltransferase in uremia

It does not signal satiety or suppress appetite-regulating hormones