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In the Danish registry-based cohort, dementia risk was reduced 11% (HR = 0.89) with yearly increased exposure to GLP-1 RAs
For this reason, the effect of Notch inhibition is not selective for L-cells, and the number of K, goblet, and Paneth cells also increases
This differs from muscle-building (where lean mass increases) and represents preservation of existing muscle during fat loss
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In a later study, Biswas et al
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