tirzepatide ozempic has a rival now: What is tirzepatide? Can You Mix Peptides Yourself

Aronne, Director of the Comprehensive Weight Control Center at Weill Cornell Medicine in New York City

specialized compounded options were used historically for flexible dosing until regulatory restrictions changed in 2025

GLP-1 Reduces appetite, slows gastric emptying GIP Enhances insulin, improves fat metabolism Glucagon Increases energy expenditure, burns fat Based on Phase 2 clinical trial data (published in NEJM, 2023), retatrutide's side effects are primarily gastrointestinal, similar to other GLP-1 agonists but with some differences due to the glucagon component

Lyophilized peptide powder should be stored at -20C, protected from light and moisture, and kept sealed until use

This is the same active ingredient in the injectable version of Wegovy and became available for private prescription in June 2026

Biol Pharm Bull 39:163173