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Nature (2002) 418(6893):419.10.1038/nature00870 55 SanzCVazquezPBlazquezCBarrioPAAlvarezMMBlazquezE

Food and Drug Administration (FDA) started mandating pharmaceutical manufacturers put an expiration date on prescription drugs as well as OTC (over-the-counter) medications and dietary/herbal supplements in the late 1970s

Mitochondrial dysfunction has emerged as a crucial factor in the pathogenesis of various diseases, including DE, highlighting the complex relationship between DE and mitochondrial dysfunction