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These effects are dose-dependentmeaning they're proportional to your starting dose leveland almost always temporary
Lean loss is a normal consequence of large, rapid weight loss on any incretin drug
The honest timeline matters here
The structural valve failure that causes varicose veins, spider veins, and chronic venous insufficiency does not reverse with weight loss alone, and GLP-1 medications are not a substitute for vein treatment
Additionally, our study found that the odds of death from any cause was 16% lower in the GLP1-RA group compared to active comparators within the same follow-up period
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