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Ali says the current evidence is pointing to the likelihood that stimulating amylin receptors doesnt do as much as the GLP-1/GIP combination that Zepbound provides

Abbreviations AD: Alzheimers disease CCK: Cholecystokinin CNS: Central nervous system CRF: Corticotropin-releasing factor DPP4i: Dipeptidyl peptidase-4 inhibitor FDA: Food and Drug Administration FOS: Fructooligosaccharides GERD: Gastroesophageal reflux disease GI: Gastrointestinal GIP: Glucose-dependent insulinotropic polypeptide GLP-1: Glucagon-like peptide-1 GLP-1 RA: Glucagon-like peptide-1 receptor agonist IPPW: Isolated pyloric pressure wave MMC: Migrating motor complex PYY: Peptide YY RCT: Randomized controlled trial SCFA: Short chain fatty acid T2DM: Type two diabetes mellitus References Yao H, et al

And third is Alabama, with 1.7 percent on GLP-1s and 6.5 percent of those with obesity

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