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It doesn't override thermodynamics
10.1002/hep.21006 27 DingZ.WangL.SunJ.ZhengL.TangY.TangH
However, ongoing research, such as the FLOW trial, which had been comparing GLP-1RAs to a placebo in patients with T2D and CKD, was recently halted prematurely due to their effectiveness
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Overall, results from the cardiovascular outcomes trials (CVOTs) completed for all marketed GLP-1 RAs in type 2 diabetes support a benefit in HF specifically in addition to the approved use in broad CVD risk reduction in people with type 2 diabetes ( The biology and pharmacology of GLP-1 GLP-1 is a major peptide hormone of the incretin system
Angelo LS, Wu JY, Meng F, Sun M, Kopetz S , McCutcheon IE , Slopis JM, Kurzrock R
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